Article
Werner Syndrome, aging and cancer.
Genome dynamics - 1 Jan 2006
Ozgenc A, Loeb L A
Abstract excerpt
Werner syndrome (WS) is a rare autosomal recessive genetic instability/cancer predisposition disorder that displays many symptoms of premature aging. The mimicry of agerelated phenotypes in WS, as well as its dependence on a single defective gene product, has provided the impetus for studying this fascinating disease as a model system for normative aging and its related pathologies such as atherosclerosis,...
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