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Article

Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2002

Ko Jinkyung, Gendron-Fitzpatrick Annette, Splitter Gary A

Abstract excerpt

IFN-gamma is a key cytokine controlling Brucella infection, and the diverse functions of this cytokine are mediated by IFN regulatory factors (IRFs) such as IRF-1, IRF-2, and IFN consensus sequence binding protein (ICSBP). However, the roles of these three IRFs in Brucella infection have not been investigated. The infection of each IRF-deficient mouse strain provides an opportunity to determine not only the...

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PMID: 11859135
DOI: 10.4049/jimmunol.168.5.2433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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