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Article

A link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients.

Lung cancer (Amsterdam, Netherlands) - 1 Mar 2002

Biros Erik, Kohút Anton, Biros Ivan, Kalina Ivan, Bogyiová Eva, Stubna Ján

Abstract excerpt

The p53 protein acts as a checkpoint in the cell cycle, either preventing or initiating apoptosis. Since cancer is the unchecked proliferation of cells, p53s role is critical. Thus, we have sought a link between the p53 polymorphisms and apoptosis. Wild-type p53 tumor suppressor gene exhibits several common single nucleotide polymorphisms (SNP) both in coding and non-coding regions. We focused on two of them, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11844595
DOI: 10.1016/s0169-5002(01)00446-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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