Article
Polymorphisms in apoptosis-related genes and TP53 mutations in non-small cell lung cancer.
Journal of Korean medical science - 1 Nov 2011
Bae Eun Young, Lee Eun Jin, Kang Hyo-Gyoung, Lee Shin Yup, Jin Gwang, Lee Won Kee, Choi Jin Eun, Jeon Hyo-Sung, Lim Jeong Ok, Lee Eung Bae, Park Jae Yong
Abstract excerpt
Apoptosis plays an essential role in the elimination of mutated or transformed cells from the body. Therefore, polymorphisms of apoptosis-related genes may lead to an alteration in apoptotic capacity, thereby affecting the occurrence of TP53 mutations in lung cancer. We investigated the relationship between potentially functional polymorphisms of apoptosis-related genes and TP53 mutations in non-small cell lung...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
