Article
Gene polymorphisms, apoptotic capacity and cancer risk.
Human genetics - 1 Apr 2009
Imyanitov Evgeny N
Abstract excerpt
Programmed cell death has been implicated in various aspects of cancer development. Apoptotic capacity is a subject of significant interindividual variations, which are largely attributed to hereditary traits. Single nucleotide polymorphisms (SNPs) located within cell death genes may influence cancer risk in various ways. Low activity of apoptosis may favor cancer development because of the failure to eliminate...
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