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Article

Identification of Fas (APO-1/CD95) and p53 gene mutations in non-small cell lung cancer.

International journal of oncology - 1 Jan 2002

Boldrini L, Faviana P, Gisfredi S, Di Quirico D, Lucchi M, Mussi A, Angeletti C A, Baldinotti F, Fogli A, Simi P, Basolo F, Pingitore F, Fontanini G

Abstract excerpt

Fas (APO-1/CD95) is a broadly expressed death receptor involved in a series of physiological and pathological apoptotic processes. One of the possible mechanisms for resistance to apoptosis signaling in the immune system as well as in the pathogenesis of non-lymphoid malignancies is the presence of Fas mutations within the entire gene. We investigated, in 79 non-small cell lung cancer (NSCLC) samples, the...

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA, Neoplasm

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Share to Genes, p53

Share to Polymorphism, Single-Stranded Conformational

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 11743657
DOI: 10.3892/ijo.20.1.155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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