Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of CYP1A1 germ line polymorphisms with mutations of the p53 gene in lung cancer.

Cancer research - 1 Jan 1996

Kawajiri K, Eguchi H, Nakachi K, Sekiya T, Yamamoto M

Abstract excerpt

We reported an association of smoking-induced lung cancer susceptibility with the human cytochrome P450 1A1 (CYP1A1) polymorphisms in our previous studies. To investigate a relationship between genetically determined individual predispositions and mutations of target genes in the early stage of lung carcinogenesis, we examined p53 mutations in relation to germ line polymorphisms of the CYP1A1 and GSTM1 genes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 Enzyme System
Share to Gene Frequency
Share to Glutathione Transferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Mutation

Share to Polymorphism, Genetic

Share to Smoking

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8548778

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of CYP1A1 germ line polymorphisms with mutations of the p53 gene in lung cancer.PMID 8548778Read ↗

p53 gene mutations, and CYP1A1 and GSTM1 genotypes in pulmonary squamous cell carcinomas.Semantic proximity Read ↗

p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.Semantic proximity Read ↗

Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer.Semantic proximity Read ↗

Influence of polymorphism at p53, CYP1A1 and GSTM1 loci on p53 mutation and association of p53 mutation with prognosis in lung cancer.Semantic proximity Read ↗

p53 mutations in lung tumors: relationship to putative susceptibility markers for cancer.Semantic proximity Read ↗

Effect of CYP1A1 MSPI polymorphism on the relationship between TP53 mutation and CDKN2A hypermethylation in non-small cell lung cancer.Semantic proximity Read ↗

Genetic polymorphisms of drug-metabolizing enzymes and lung cancer susceptibility.Semantic proximity Read ↗

Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer.Semantic proximity Read ↗

Risk for K-ras gene mutations in smoking-induced lung cancer is associated with cytochrome P4501A1 and glutathione S-transferase micro1 polymorphisms.Semantic proximity Read ↗

The role of CYP1A1 Msp1 gene polymorphisms on lung cancer development in Turkey.Semantic proximity Read ↗

Genetic polymorphism of xenobiotic metabolising enzymes in Slovenian lung cancer patients.Semantic proximity Read ↗

Germ line polymorphisms of the tumor suppressor gene p53 and lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.