Article
P53 polymorphisms and haplotypes in lung cancer.
Carcinogenesis - 1 Sept 1995
Birgander R, Själander A, Rannug A, Alexandrie A K, Sundberg M I, Seidegård J, Tornling G, Beckman G, Beckman L
Abstract excerpt
An association between the BstU I 1-1 (Pro-Pro) genotype of the p53 codon 72 polymorphism and lung cancer has previously been reported by Kawajiri et al. A reanalysis of the data by Kawajiri et al. revealed no significant difference between patients and controls with respect to allele frequencies, and the increased frequency of BstU I 1-1 homozygotes was mostly ascribable to a deviation from the Hardy-Weinberg...
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