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Article

A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances.

Molecular psychiatry - 1 Jan 2002

Schinka J A, Town T, Abdullah L, Crawford F C, Ordorica P I, Francis E, Hughes P, Graves A B, Mortimer J A, Mullan M

Abstract excerpt

Genetic association studies investigating the role of the +118A allele of the human mu-opioid receptor gene in risk for alcohol dependency have produced inconsistent findings, possibly because of the failure to recognize sampling methodology difficulties inherent in association studies of polygenic disorders. We examined the frequency of the AA genotype and A allele in several groups of substance-dependent cases,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11840318
DOI: 10.1038/sj.mp.4000951

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances.PMID 11840318Read ↗

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