No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case-control sample.

doi:10.1016/j.drugalcdep.2010.12.026

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Article

No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case-control sample.

Drug and alcohol dependence - 1 Aug 2011

Nikolov Momchil A, Beltcheva Olga, Galabova Antoaneta, Ljubenova Anna, Jankova Elena, Gergov Galin, Russev Atanas A, Lynskey Michael T, Nelson Elliot C, Nesheva Eleonora, Krasteva Dorita, Lazarov Philip, Mitev Vanio I, Kremensky Ivo M, Kaneva Radka P, Todorov Alexandre A

Abstract excerpt

The μ-opioid receptor is the primary site of action of most opioids. The 118A>G (rs1799971) polymorphism in exon 1 of the μ-opioid receptor gene (OPRM1) leads to an Asn40Asp amino acid change that affects a putative N-glycosylation site. It has been widely investigated for association with alcoho...

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Identifiers

PMID: 21277709
DOI: 10.1016/j.drugalcdep.2010.12.026
PMCID: PMC3128690

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21277709-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case-control sample.PMID 21277709Read ↗

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