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Article

Pharmacogenomics of the human µ-opioid receptor.

Pharmacogenomics - 1 Sept 2011

Kasai Shinya, Ikeda Kazutaka

Abstract excerpt

The µ-opioid receptor is a primary target for clinically important opioid analgesics, including morphine, fentanyl and methadone. Many genetic variations have been identified in the human µ-opioid receptor MOP gene (OPRM1), and their implications have been reported in the effects of opioid drugs and susceptibility to drug dependence. Interestingly, agonistic and antagonistic opioid effects are inversely...

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Source

Identifiers

PMID: 21919606
DOI: 10.2217/pgs.11.68

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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