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Article

Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2005

Bart Gavin, Kreek Mary Jeanne, Ott Jurg, LaForge K Steven, Proudnikov Dmitri, Pollak Lotta, Heilig Markus

Abstract excerpt

The mu-opioid receptor (MOR), through its effects on reward and stress-responsivity, modulates alcohol intake in both animal and human laboratory studies. We have previously demonstrated that the frequently occurring A118G single-nucleotide polymorphism (SNP) in exon 1 of the MORgene (OPRM1), which encodes an amino-acid substitution, is functional and receptors encoded by the variant 118G allele bind the...

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Source

Identifiers

PMID: 15525999
DOI: 10.1038/sj.npp.1300598

Genes

OPRM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden.PMID 15525999Read ↗

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