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Article

μ-Opioid receptor gene (OPRM1) polymorphism A118G: lack of association in Finnish populations with alcohol dependence or alcohol consumption.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000

Rouvinen-Lagerström Noora, Lahti Jari, Alho Hannu, Kovanen Leena, Aalto Mauri, Partonen Timo, Silander Kaisa, Sinclair David, Räikkönen Katri, Eriksson Johan G, Palotie Aarno, Koskinen Seppo, Saarikoski Sirkku T

Abstract excerpt

AIMS: The molecular epidemiological studies on the association of the opioid receptor µ-1 (OPRM1) polymorphism A118G (Asn40Asp, rs1799971) and alcohol use disorders have given conflicting results. The aim of this study was to test the possible association of A118G polymorphism and alcohol use disorders and alcohol consumption in three large cohort-based study samples. METHODS: The association between the OPRM1...

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Alcohol Drinking
Alcoholism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Population Surveillance

Receptors, Opioid, mu

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Open in PubMed Open full text

Identifiers

PMID: 23729673
DOI: 10.1093/alcalc/agt050
PMCID: PMC4296254

Genes

OPRM1

Variants

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μ-Opioid receptor gene (OPRM1) polymorphism A118G: lack of association in Finnish populations with alcohol dependence or alcohol consumption.PMID 23729673Read ↗

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Possible association between OPRM1 genetic variance at the 118 locus and alcohol dependence in a large treatment sample: relationship to alcohol dependence symptoms.Semantic proximity Read ↗

Lack of associations of the opioid receptor mu 1 (OPRM1) A118G polymorphism (rs1799971) with alcohol dependence: review and meta-analysis of retrospective controlled studies.Semantic proximity Read ↗

The OPRM1 A118G polymorphism: converging evidence against associations with alcohol sensitivity and consumption.Semantic proximity Read ↗

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A systematic review of the A118G (Asn40Asp) variant of OPRM1 in relation to smoking initiation, nicotine dependence and smoking cessation.Semantic proximity Read ↗

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