Article
Association between a serotonin transporter promoter region polymorphism and mood response during tryptophan depletion.
Molecular psychiatry - 1 Jan 2002
Moreno F A, Rowe D C, Kaiser B, Chase D, Michaels T, Gelernter J, Delgado P L
Abstract excerpt
This study investigated the relationship between depressive symptom response during tryptophan (TRP) depletion and a functional polymorphism of the promoter region of the serotonin (5-HT) transporter gene (SLC6A4).(1) Forty-three subjects in remission from a major depressive episode who underwent TRP depletion were genotyped. DNA was extracted from blood lymphocytes or from cheek cells.(2) The two common alleles...
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