Article
Functional polymorphism in the serotonin transporter promoter at the SLC6A4 locus and mood disorders.
Biological psychiatry - 1 Oct 1998
Ohara K, Nagai M, Tsukamoto T, Tani K, Suzuki Y, Ohara K
Abstract excerpt
BACKGROUND: Heils et al found a functional polymorphism in the transcriptional control region upstream of the serotonin transporter gene at the SLC6A4 locus. The transcriptional promoter activity of the short (s) form was less than twice that of the long (l) form of the serotonin transporter prom...
Topics
- Adult
- Alleles
- Carrier Proteins
- Chromosomes, Human, Pair 17
- Female
- Genotype
- Humans
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Mood Disorders
- Nerve Tissue Proteins
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Serotonin Plasma Membrane Transport Proteins