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Article

Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression.

Archives of general psychiatry - 1 Jul 2007

Hu Xian-Zhang, Rush A John, Charney Dennis, Wilson Alexander F, Sorant Alexa J M, Papanicolaou George J, Fava Maurizio, Trivedi Madhukar H, Wisniewski Stephen R, Laje Gonzalo, Paddock Silvia, McMahon Francis J, Manji Husseini, Lipsky Robert H

Abstract excerpt

CONTEXT: The HTTLPR, a functional polymorphism of the serotonin transporter gene solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4), promoter, affects transcription and may be involved in antidepressant drug treatment outcome, although response rates with antidepressants can be lower in patients who experience adverse effects. OBJECTIVE: To test the hypothesis that HTTLPR is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17606812
DOI: 10.1001/archpsyc.64.7.783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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