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Article

Serotonin transporter gene-linked polymorphic region: possible pharmacogenetic implications of rare variants.

Psychiatric genetics - 1 Aug 2006

Smeraldi Enrico, Serretti Alessandro, Artioli Paola, Lorenzi Cristina, Catalano Marco

Abstract excerpt

A functional insertion/deletion (*l/*s) repeat polymorphism within the promoter region of the serotonin transporter (5-HTTLPR) has been described. An association between *l variant and a better and faster response to serotonin selective reuptake inhibitors in depressed patients was reported in Caucasians. The value of the explained variance due to the 5-HTTLPR, however, was 7% only, and different *l and *s...

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PMID: 16829782
DOI: 10.1097/01.ypg.0000218611.53064.a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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