Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antidepressant response and the serotonin transporter gene-linked polymorphic region.

Biological psychiatry - 15 Sept 2010

Taylor Matthew J, Sen Srijan, Bhagwagar Zubin

Abstract excerpt

BACKGROUND: The serotonin transporter gene-linked polymorphic region (5-HTTLPR) has been proposed as a predictor of antidepressant response. Insertion or deletion of a 44-base pair-long region gives rise to short "S" and long "L" forms of the promoter region, the "S" form being associated with reduced serotonin transporter expression. METHODS: A systematic review and meta-analysis was performed to clarify the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Antidepressive Agents
Share to Depressive Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Remission Induction

Share to Serotonin Plasma Membrane Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20615496
DOI: 10.1016/j.biopsych.2010.04.034
PMCID: PMC2929304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antidepressant response and the serotonin transporter gene-linked polymorphic region.PMID 20615496Read ↗

5-HTTLPR modulates antidepressant efficacy in depressed women.Semantic proximity Read ↗

Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy.Semantic proximity Read ↗

Serotonin transporter promoter gene polymorphism and long-term outcome of antidepressant treatmentSemantic proximity Read ↗

Association between serotonin transporter-linked polymorphic region and escitalopram antidepressant treatment response in Korean patients with major depressive disorder.Semantic proximity Read ↗

Role of serotonin transporter and receptor gene polymorphisms in treatment response to selective serotonin reuptake inhibitors in major depressive disorder.Semantic proximity Read ↗

Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression.Semantic proximity Read ↗

Serotonin transporter (5-HTT) promoter genotype may influence the prolactin response to clomipramine.Semantic proximity Read ↗

Effects of serotonin transporter promoter polymorphisms on serotonin function.Semantic proximity Read ↗

Pharmacogenetic association of bi- and triallelic polymorphisms of SLC6A4 with antidepressant response in major depressive disorder.Semantic proximity Read ↗

Serotonin transporter polymorphism (5-HTTLPR) and citalopram effectiveness and side effects in children with depression and/or anxiety disorders.Semantic proximity Read ↗

Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression.Semantic proximity Read ↗

Serotonin transporter gene polymorphism and antidepressant response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.