Article
Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets.
American journal of medical genetics - 5 Feb 1999
Greenberg B D, Tolliver T J, Huang S J, Li Q, Bengel D, Murphy D L
Abstract excerpt
The human serotonin transporter (5-HTT), encoded by a single gene on chromosome 17q11.2, is expressed in brain and blood cells. 5-HTT is implicated in mood and anxiety regulation, and is where antidepressant and antianxiety drugs initially act in the brain. A 5-HTT-linked promoter region (5-HTTLP...
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