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Article

Tryptophan supplementation and serotonin function: genetic variations in behavioural effects.

The Proceedings of the Nutrition Society - 1 May 2018

Gibson E L

Abstract excerpt

The neurotransmitter serotonin has a role in affective disorders such as depression and anxiety, as well as sleep, cognitive function and appetite. This review examines the evidence that serotonin-related genotypes may moderate the behavioural effects of supplementation with the serotonin precursor amino acid l-tryptophan (TRP), on which synthesis of serotonin (or 5-hydroxytryptamine; 5-HT) depends. However, 95 %...

Topics

Affect
Alleles
Behavior
Depression
Dietary Supplements
Female
Genetic Variation
Genotype
Humans
Hydrocortisone
Male
Receptors, Serotonin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serotonin

Stress, Psychological

Tryptophan

Source

Identifiers

PMID: 29368666
DOI: 10.1017/S0029665117004451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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