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Article

Tryptophan supplementation and serotonin function: genetic variations in behavioural effects.

The Proceedings of the Nutrition Society - 1 May 2018

Gibson E L

Abstract excerpt

The neurotransmitter serotonin has a role in affective disorders such as depression and anxiety, as well as sleep, cognitive function and appetite. This review examines the evidence that serotonin-related genotypes may moderate the behavioural effects of supplementation with the serotonin precursor amino acid l-tryptophan (TRP), on which synthesis of serotonin (or 5-hydroxytryptamine; 5-HT) depends. However, 95 %...

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Identifiers

PMID: 29368666
DOI: 10.1017/S0029665117004451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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