Article
Association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioral responses to tryptophan depletion in healthy women with and without family history of depression.
Archives of general psychiatry - 1 Jul 2002
Neumeister Alexander, Konstantinidis Anastasios, Stastny Juergen, Schwarz Markus J, Vitouch Oliver, Willeit Matthaus, Praschak-Rieder Nicole, Zach Johanna, de Zwaan Martina, Bondy Brigitta, Ackenheil Manfred, Kasper Siegfried
Abstract excerpt
BACKGROUND: Evidence suggests that serotonin transporter gene promoter polymorphism (5HTTLPR)-dependent low transcriptional activity of the human serotonin transporter gene may be a genetic susceptibility factor for depression. We studied the behavioral responses to tryptophan depletion (TD) in healthy women with and without a first-degree family history of depression and examined the relationship to 5HTTLPR...
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