Article
Coeliac disease: follow-up linkage study provides further support for existence of a susceptibility locus on chromosome 11p11.
Annals of human genetics - 1 Jul 2001
King A L, Fraser J S, Moodie S J, Curtis D, Dearlove A M, Ellis H J, Rosen-Bronson S, Ciclitira P J
Abstract excerpt
Susceptibility to coeliac disease has a strong genetic component. The HLA associations have been well described but it is clear that other genes outside this region must also be involved in disease development. Two previous genome-wide linkage studies using the affected sib pair method produced conflicting results. Our own family based linkage study of 16 highly informative pedigrees identified 17 possibly linked...
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