Article
Haplotype variation at the IBD5/SLC22A4 locus (5q31) in coeliac disease in the Irish population.
Tissue antigens - 1 Aug 2004
Ryan A W, Thornton J M, Brophy K, Daly J S, O'Morain C, McLoughlin R M, Kennedy N P, Abuzakouk M, Stevens F M, Feighery C, Kelleher D, McManus R
Abstract excerpt
In addition to the well-established association of coeliac disease (CD) with HLA-DQ (6p21) and possibly CTLA4 (2q33), there is considerable evidence for a susceptibility locus on chromosome 5q, which contains many potential candidates for inflammatory disease, including a cluster of cytokine genes in 5q31. CD cases and controls were genotyped for four single-nucleotide polymorphism (SNP) markers that together...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.