Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors.

doi:10.1111/j.1600-0854.2007.00634.x

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Article

Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors.

Traffic (Copenhagen, Denmark) - 1 Nov 2007

Casanova James E

Abstract excerpt

The ADP ribosylation factors (Arfs) are a family of small, ubiquitously expressed and evolutionarily conserved guanosine triphosphatases that are key regulators of vesicular transport in eukaryotic cells (D'Souza-Schorey C, Chavrier P. ARF proteins: roles in membrane traffic and beyond. Nat Rev Mol Cell Biol 2006;7:347-358). Although Arfs are best known for their role in the nucleation of coat protein assembly at...

Topics

ADP-Ribosylation Factors
Animals
Biochemistry
Brefeldin A
Catalytic Domain
Cell Nucleus
Gene Expression Regulation
Guanine Nucleotide Exchange Factors
Guanosine Triphosphate
Humans
Mutation
Nerve Tissue Proteins
Protein Isoforms
Protein Structure, Tertiary
Tissue Distribution

Source

Open in PubMed

Identifiers

PMID: 17850229
DOI: 10.1111/j.1600-0854.2007.00634.x

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