Article
Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors.
Traffic (Copenhagen, Denmark) - 1 Nov 2007
Casanova James E
Abstract excerpt
The ADP ribosylation factors (Arfs) are a family of small, ubiquitously expressed and evolutionarily conserved guanosine triphosphatases that are key regulators of vesicular transport in eukaryotic cells (D'Souza-Schorey C, Chavrier P. ARF proteins: roles in membrane traffic and beyond. Nat Rev Mol Cell Biol 2006;7:347-358). Although Arfs are best known for their role in the nucleation of coat protein assembly at...
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