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Article

Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.

Science (New York, N.Y.) - 29 Mar 2002

Winston William M, Molodowitch Christina, Hunter Craig P

Abstract excerpt

Double-stranded RNA-mediated gene interference (RNAi) in Caenorhabditis elegans systemically inhibits gene expression throughout the organism. To investigate how gene-specific silencing information is transmitted between cells, we constructed a strain that permits visualization of systemic RNAi. We used this strain to identify systemic RNA interference-deficient (sid) loci required to spread gene-silencing...

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PMID: 11834782
DOI: 10.1126/science.1068836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.PMID 11834782Read ↗

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