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Article

SID-2 negatively regulates development likely independent of nutritional dsRNA uptake.

RNA biology - 1 Jun 2021

Braukmann Fabian, Jordan David, Jenkins Benjamin, Koulman Albert, Miska Eric Alexander

Abstract excerpt

RNA interference (RNAi) is a gene regulatory mechanism based on RNA-RNA interaction conserved through eukaryotes. Surprisingly, many animals can take-up human-made double stranded RNA (dsRNA) from the environment to initiate RNAi suggesting a mechanism for dsRNA-based information exchange between organisms and their environment. However, no naturally occurring example has been identified since the discovery of...

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Identifiers

PMID: 33044912
DOI: 10.1080/15476286.2020.1827619
PMCID: PMC8081039

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