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Article

Inducible systemic RNA silencing in Caenorhabditis elegans.

Molecular biology of the cell - 1 Jul 2003

Timmons Lisa, Tabara Hiroaki, Mello Craig C, Fire Andrew Z

Abstract excerpt

Introduction of double-stranded RNA (dsRNA) can elicit a gene-specific RNA interference response in a variety of organisms and cell types. In many cases, this response has a systemic character in that silencing of gene expression is observed in cells distal from the site of dsRNA delivery. The molecular mechanisms underlying the mobile nature of RNA silencing are unknown. For example, although cellular entry of...

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Identifiers

PMID: 12857879
DOI: 10.1091/mbc.e03-01-0858
PMCID: PMC165691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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