Article

Characterization of SID-1-dependent and independent intergenerational RNA transport pathways in <i>Caenorhabditis elegans</i>

2017-06-26

Abstract excerpt

Systemic RNA interference (RNAi) in C. elegans is dependent on sid-1 (W inston et al. 2002), sid-3 (J ose et al. 2012) and sid-5 (H inas et al. 2012). After injection, expression, or ingestion, double-stranded RNA (dsRNA) is transported between cells throughout the animal to enable RNAi in most tissues, including the germline and progeny. Here, we characterize the role of the Sid genes in transport of dsRNA...

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Literature Corpus work: 48585ffa-4c70-554c-a88d-f137d523c2c3
DOI: 10.1101/156232

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