Article

Intergenerational transport of double-stranded RNA in <i>C. elegans</i> can limit heritable epigenetic changes

2021-10-06

Abstract excerpt

<h4>ABSTRACT</h4> RNAs in circulation carry sequence-specific regulatory information between cells in plant, animal, and host-pathogen systems. Such RNA can cross generational boundaries, as evidenced by somatic double-stranded RNA (dsRNA) in the nematode C. elegans silencing genes of matching sequence in progeny. Here we dissect the intergenerational path taken by dsRNA from parental circulation and discover th...

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Literature Corpus work: 3fe69d89-ea99-5632-8496-935728206118
DOI: 10.1101/2021.10.05.463267

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