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Article

Caenorhabditis elegans SID-2 is required for environmental RNA interference.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jun 2007

Winston William M, Sutherlin Marie, Wright Amanda J, Feinberg Evan H, Hunter Craig P

Abstract excerpt

In plants and in the nematode Caenorhabditis elegans, an RNAi signal can trigger gene silencing in cells distant from the site where silencing is initiated. In plants, this signal is known to be a form of dsRNA, and the signal is most likely a form of dsRNA in C. elegans as well. Furthermore, in C. elegans, dsRNA present in the environment or expressed in ingested bacteria is sufficient to trigger RNAi...

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Identifiers

PMID: 17563372
DOI: 10.1073/pnas.0611282104
PMCID: PMC1965553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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