Article

Systemic RNA interference-defective (SID) genes modulate dopaminergic neurodegeneration in <i>C. elegans</i>

2022-02-24

Abstract excerpt

The fine-tuning of gene expression is critical for all cellular processes; aberrations in this activity can lead to pathology, and conversely, resilience. As their role in coordinating organismal responses to both internal and external factors have increasingly come into focus, small non-coding RNAs have emerged as an essential component to disease etiology. Using Systemic RNA interference Defective (SID) mutants...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 26031922-d36f-5895-8ce3-c08e71179532
DOI: 10.1101/2022.02.23.481573

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Systemic RNA interference-defective (SID) genes modulate dopaminergic neurodegeneration in <i>C. elegans</i>DOI 10.1101/2022.02.23.481573Read

Systemic RNA Interference Defective (SID) genes modulate dopaminergic neurodegeneration in C. elegansSemantic proximity Read

Integrated Regulation of Dopaminergic and Epigenetic Effectors of Neuroprotection in Parkinson’s Disease ModelsSemantic proximity Read

C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During AgingSemantic proximity Read

Found in Translation: The Utility of C. elegans Alpha-Synuclein Models of Parkinson’s DiseaseSemantic proximity Read

Attenuation of Dopaminergic Neurodegeneration in a <em>C. elegans</em> Parkinson’s Model through Regulation of Xanthine Dehydrogenase (XDH-1) Expression by the RNA Editase, ADR-2Semantic proximity Read

Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease modelSemantic proximity Read

<i>C. elegans</i> genetic background modifies the core transcriptional response in an α-synuclein model of Parkinson’s diseaseSemantic proximity Read

Functional Screening of Parkinson’s Disease Susceptibility Genes to Identify Novel Modulators of α-Synuclein Neurotoxicity in Caenorhabditis elegansSemantic proximity Read

Studying the mechanisms of neurodegeneration: C. elegans advantages and opportunitiesSemantic proximity Read

Modulation of Alpha-synuclein Expression and Associated Effects by MicroRNA Let-7 in Transgenic C. elegansSemantic proximity Read

A Systematic RNAi Screen of Neuroprotective Genes Identifies Novel Modulators of Alpha-Synuclein-Associated Effects in Transgenic Caenorhabditis elegansSemantic proximity Read

Systematic Review of Caenorhabditis elegans Models for Mechanism Research and Drug Discovery in Parkinson’s DiseaseSemantic proximity Read