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Article

Flow cytometric determination of HPRT-variants in human peripheral blood lymphocytes.

Mutation research - 29 Jan 2002

Kotova Natalia, Grawé Jan

Abstract excerpt

Hypoxanthine guanine phosphoribosyl transferase (HPRT) deficient human peripheral blood lymphocytes are usually enumerated either by the cloning assay or by the autoradiographic short-term assay. The short-term approach presented here is based on flow cytometric (FCM) scoring of 6-thioguanine (6-TG) resistant lymphocytes. HPRT-variants are enumerated on the basis of both DNA synthesis (by use of immunofluorescent...

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Source

Identifiers

PMID: 11804605
DOI: 10.1016/s0027-5107(01)00269-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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