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Article

The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes.

Journal of cell science - 1 Jan 2002

Obermüller Stefanie, Kiecke Christina, von Figura Kurt, Höning Stefan

Abstract excerpt

Lamp 1 and lysosomal acid phosphatase (LAP) are lysosomal membrane proteins that harbour a tyrosine-based sorting motif within their short cytoplasmic tails. Lamp 1 is delivered from the trans-Golgi network (TGN) via endosomes directly to lysosomes bypassing the plasma membrane, whereas LAP is in...

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Identifiers

PMID: 11801736
DOI: 10.1242/jcs.115.1.185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11801736-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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