Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways.

Molecular biology of the cell - 1 Jan 2009

Donoso Maribel, Cancino Jorge, Lee Jiyeon, van Kerkhof Peter, Retamal Claudio, Bu Guojun, Gonzalez Alfonso, Cáceres Alfredo, Marzolo María-Paz

Abstract excerpt

Low-density lipoprotein receptor-related protein 1 (LRP1) is an endocytic recycling receptor with two cytoplasmic tyrosine-based basolateral sorting signals. Here we show that during biosynthetic trafficking LRP1 uses AP1B adaptor complex to move from a post-TGN recycling endosome (RE) to the basolateral membrane. Then it recycles basolaterally from the basolateral sorting endosome (BSE) involving recognition by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Polarity
Share to Endosomes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Golgi Apparatus

Share to Low Density Lipoprotein Receptor-Related Protein-1

Share to Protein Sorting Signals

Share to trans-Golgi Network

Share to Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19005208
DOI: 10.1091/mbc.e08-08-0805
PMCID: PMC2613102

Genes

LRP1
SNX17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways.PMID 19005208Read ↗

Apical trafficking in epithelial cells: signals, clusters and motorsSemantic proximity Read ↗

Polarized transport of Alzheimer amyloid precursor protein is mediated by adaptor protein complex AP1-1B.Semantic proximity Read ↗

Galectin-4-mediated transcytosis of transferrin receptor.Semantic proximity Read ↗

Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells.Semantic proximity Read ↗

Basolateral sorting of the coxsackie and adenovirus receptor through interaction of a canonical YXXPhi motif with the clathrin adaptors AP-1A and AP-1B.Semantic proximity Read ↗

ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells.Semantic proximity Read ↗

Presynaptic precursor vesicles originate from the <i>trans</i> -Golgi network, promoted by the small GTPase RAB2Semantic proximity Read ↗

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1.Semantic proximity Read ↗

Retrograde transport defects in <i>Munc18-1</i> null neurons explain abnormal Golgi morphologySemantic proximity Read ↗

The tyrosine-based lysosomal targeting signal in lamp-1 mediates sorting into Golgi-derived clathrin-coated vesicles.Semantic proximity Read ↗

The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway.Semantic proximity Read ↗

The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.