Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic association in large pedigrees.

Genetic epidemiology - 1 Jan 2001

Gutin A, Abkevich V, Camp N J, Farnham J M, Cannon-Albright L, Thomas A

Abstract excerpt

We subjected the first replication of the simulated isolated population data set to a novel analysis for association between marker alleles and either disease phenotypes or quantitative variable. The analysis depends on being able to reliably reconstruct all haplotypes in the pedigree. This was achieved using the MCLINK blocked Gibbs sampling program. We observed a highly significant association between the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Genetic Markers
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Likelihood Functions

Share to Lod Score

Share to Mathematical Computing

Share to Quantitative Trait, Heritable

Share to Software

Source

Identifiers

PMID: 11793740
DOI: 10.1002/gepi.2001.21.s1.s571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic association in large pedigrees.PMID 11793740Read ↗

The role of large pedigrees in an era of high-throughput sequencing.Semantic proximity Read ↗

Association testing of the mitochondrial genome using pedigree data.Semantic proximity Read ↗

Evaluating power and type 1 error in large pedigree analyses of binary traits.Semantic proximity Read ↗

Pedigree-Defined Haplotypes and Their Applications to Genetic Studies.Semantic proximity Read ↗

Estimating haplotype relative risks in complex disease from unphased SNPs data in families using a likelihood adjusted for ascertainment.Semantic proximity Read ↗

Detecting linkage for a complex disease using simulated extended pedigrees.Semantic proximity Read ↗

Combined linkage and association analysis in pedigrees.Semantic proximity Read ↗

The value of molecular haplotypes in a family-based linkage study.Semantic proximity Read ↗

Comparison of association mapping methods in a complex pedigreed population.Semantic proximity Read ↗

Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.Semantic proximity Read ↗

Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease.Semantic proximity Read ↗

Characterizing allelic associations from unphased diploid data by graphical modeling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.