Article
Combined linkage and association analysis in pedigrees.
Genetic epidemiology - 1 Jan 2001
Siegmund K D, Vora H, Gauderman W J
Abstract excerpt
We applied a combined linkage and association model for quantitative traits in pedigrees to identify possible functional polymorphisms and to test for association resulting from population stratification and admixture. Functional polymorphisms are identified as variants that are significantly associated with a trait (high chi 2 value) and showing no residual evidence of linkage (low lod score). Applying our model...
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