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Article

Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease.

Genome research - 1 Jan 2001

Fallin D, Cohen A, Essioux L, Chumakov I, Blumenfeld M, Cohen D, Schork N J

Abstract excerpt

There is growing debate over the utility of multiple locus association analyses in the identification of genomic regions harboring sequence variants that influence common complex traits such as hypertension and diabetes. Much of this debate concerns the manner in which one can use the genotypic information from individuals gathered in simple sampling frameworks, such as the case/control designs, to actually...

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Identifiers

PMID: 11156623
DOI: 10.1101/gr.148401
PMCID: PMC311030

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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