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Article

To type or not to type: the use of unaffected siblings in nonparametric linkage analysis.

Genetic epidemiology - 1 Jan 2001

Majewski J

Abstract excerpt

Unaffected individuals are often disregarded in nonparametric linkage analysis. Because of the presumed high complexity of genetic interactions and the resulting low penetrance of any single genetic effect, the statistical contribution of unaffected sib pairs is thought to be considerably lower than that of the affected. However, in cases where a large number of unaffected family members are available for...

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Identifiers

PMID: 11793730
DOI: 10.1002/gepi.2001.21.s1.s522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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