Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship estimation in affected sib pair analysis of late-onset diseases.

European journal of human genetics : EJHG - 1 Jan 2000

Göring H H, Ott J

Abstract excerpt

In linkage studies, errors in pedigree structure will often be uncovered through Mendelian inconsistencies. In affected sib pair analysis of diseases with late onset, however, such mistakes will usually go undetected since parental genotypes are commonly not known. Cases of nonpaternity, unrecorded adoption or accidental sample swap in the laboratory will then not be noticed. Typically, such relationship errors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Diseases, Inborn
Share to Genetic Linkage
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Models, Genetic

Share to Models, Statistical

Share to Pedigree

Share to Software

Source

Identifiers

PMID: 9195155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship estimation in affected sib pair analysis of late-onset diseases.PMID 9195155Read ↗

Accurate inference of relationships in sib-pair linkage studies.Semantic proximity Read ↗

Statistical properties of affected sib-pair linkage tests.Semantic proximity Read ↗

Linkage analysis for diseases with variable age of onset.Semantic proximity Read ↗

A test statistic to detect errors in sib-pair relationships.Semantic proximity Read ↗

Power, validity, bias and robustness of family-based association analysis methods in the presence of linkage for late onset diseases.Semantic proximity Read ↗

A robust identity-by-descent procedure using affected sib pairs: multipoint mapping for complex diseases.Semantic proximity Read ↗

Efficiency of typing unaffected relatives in an affected-sib-pair linkage study with single-locus and multiple tightly linked markers.Semantic proximity Read ↗

Extensions to sib-pair linkage tests applicable to disorders characterized by delayed onset.Semantic proximity Read ↗

A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test.Semantic proximity Read ↗

Model-Free Linkage Analysis of a Binary Trait.Semantic proximity Read ↗

Using risk calculation to implement an extended relative pair analysis.Semantic proximity Read ↗

Improved inference of relationship for pairs of individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.