Article
Relationship estimation in affected sib pair analysis of late-onset diseases.
European journal of human genetics : EJHG - 1 Jan 2000
Göring H H, Ott J
Abstract excerpt
In linkage studies, errors in pedigree structure will often be uncovered through Mendelian inconsistencies. In affected sib pair analysis of diseases with late onset, however, such mistakes will usually go undetected since parental genotypes are commonly not known. Cases of nonpaternity, unrecord...
Topics
- Bayes Theorem
- Data Interpretation, Statistical
- Decision Making
- Factor Analysis, Statistical
- Genetic Diseases, Inborn
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Models, Genetic
- Models, Statistical
- Pedigree