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Article

Power of affected sibling method tests for linkage.

Human heredity - 1 Jan 2000

Tierney C, McKnight B

Abstract excerpt

When the mode of inheritance of a disease susceptibility (DS) gene is unknown, the affected sibling method can be applied to study whether a DS gene and a marker gene are linked. This method considers how k affected siblings (k > or = 2) share marker alleles identically by descent from their parents. Several nonparametric and likelihood ratio test statistics have been proposed for the use with affected sibling...

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PMID: 8406516
DOI: 10.1159/000154145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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