Article
Deviations from hardy-weinberg equilibrium in parental and unaffected sibling genotype data.
Human heredity - 1 Jan 2009
Li Bingshan, Leal Suzanne M
Abstract excerpt
BACKGROUND: Genotyping error can increase both type I and II errors. In order to elucidate potential genotyping errors, data quality control often includes testing genotype data for deviations from Hardy-Weinberg Equilibrium (HWE). METHODS: The Hardy-Weinberg Disequilibrium (HWD) coefficient and the ability to reject the null hypothesis of HWE were calculated analytically for genotype data from parents and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
