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Article

Genome-wide analysis reveals a cell cycle-dependent mechanism controlling centromere propagation.

The Journal of cell biology - 1 Dec 2008

Erhardt Sylvia, Mellone Barbara G, Betts Craig M, Zhang Weiguo, Karpen Gary H, Straight Aaron F

Abstract excerpt

Centromeres are the structural and functional foundation for kinetochore formation, spindle attachment, and chromosome segregation. In this study, we isolated factors required for centromere propagation using genome-wide RNA interference screening for defects in centromere protein A (CENP-A; cent...

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Identifiers

PMID: 19047461
DOI: 10.1083/jcb.200806038
PMCID: PMC2592830

Genes

APC
CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19047461-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genome-wide analysis reveals a cell cycle-dependent mechanism controlling centromere propagation.PMID 19047461Read ↗

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