Article
Contribution of CAF-I to anaphase-promoting-complex-mediated mitotic chromatin assembly in Saccharomyces cerevisiae.
Eukaryotic cell - 1 Apr 2005
Harkness Troy A A, Arnason Terra G, Legrand Charmaine, Pisclevich Marnie G, Davies Gerald F, Turner Emma L
Abstract excerpt
The anaphase-promoting complex (APC) is required for mitotic progression and genomic stability. Recently, we demonstrated that the APC is also required for mitotic chromatin assembly and longevity. Here, we investigated the role the APC plays in chromatin assembly. We show that apc5(CA) mutations genetically interact with the CAF-I genes as well as ASF1, HIR1, and HIR2. When present in multiple copies, the...
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