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Article

Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway.

The Journal of cell biology - 6 Jan 2003

Goshima Gohta, Kiyomitsu Tomomi, Yoda Kinya, Yanagida Mitsuhiro

Abstract excerpt

Kinetochores are the chromosomal sites for spindle interaction and play a vital role for chromosome segregation. The composition of kinetochore proteins and their cellular roles are, however, poorly understood in higher eukaryotes. We identified a novel kinetochore protein family conserved from yeast to human that is essential for equal chromosome segregation. The human homologue hMis12 of yeast spMis12/scMtw1...

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Identifiers

PMID: 12515822
DOI: 10.1083/jcb.200210005
PMCID: PMC2172742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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