Article
Overlapping regulation of CenH3 localization and histone H3 turnover by CAF-1 and HIR proteins in Saccharomyces cerevisiae.
Genetics - 1 Jan 2011
Lopes da Rosa Jessica, Holik John, Green Erin M, Rando Oliver J, Kaufman Paul D
Abstract excerpt
Accurate chromosome segregation is dependent on the centromere-specific histone H3 isoform known generally as CenH3, or as Cse4 in budding yeast. Cytological experiments have shown that Cse4 appears at extracentromeric loci in yeast cells deficient for both the CAF-1 and HIR histone H3/H4 deposit...
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