Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Case of interstitial 12q deletion in association with Wilms tumor.

American journal of medical genetics - 1 Dec 2001

Rapley E A, Hargrave D, Persinguhe N, Barfoot R, Moore I, Radford M, Stratton M R, Rahman N, Pritchard-Jones K

Abstract excerpt

A 14-month-old boy presenting with Wilms tumor (WT) was found to have a small de novo deletion of the long arm of chromosome 12 (12q11-12q13.11). Microsatellite analysis of this region from constitutional DNA showed that the paternal allele was absent between the markers D12S331 and D12S1713 (inclusive). In the WT there was no evidence of loss of the maternal chromosome. Constitutional chromosome abnormalities...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 12

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Family Health

Share to Infant

Share to Lod Score

Share to Microsatellite Repeats

Share to Wilms Tumor

Source

Identifiers

PMID: 11754052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Case of interstitial 12q deletion in association with Wilms tumor.PMID 11754052Read ↗

Loss of heterozygosity at 11p13 in Wilms' tumours does not necessarily involve mutations in the WT1 gene.Semantic proximity Read ↗

Allelotyping in Wilms tumors identifies a putative third tumor suppressor gene on chromosome 11.Semantic proximity Read ↗

Allele loss in Wilms tumors of chromosome arms 11q, 16q, and 22q correlate with clinicopathological parameters.Semantic proximity Read ↗

Loss of heterozygosity in Wilms' tumors, studied for six putative tumor suppressor regions, is limited to chromosome 11.Semantic proximity Read ↗

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor.Semantic proximity Read ↗

Evidence for susceptibility genes to familial Wilms tumour in addition to WT1, FWT1 and FWT2.Semantic proximity Read ↗

A third Wilms' tumor locus on chromosome 16q.Semantic proximity Read ↗

Linkage of familial Wilms' tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors.Semantic proximity Read ↗

Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome.Semantic proximity Read ↗

Constitutional and somatic deletions of two different regions of maternal chromosome 11 in Wilms tumor.Semantic proximity Read ↗

Direct pulsed field gel electrophoresis of Wilms' tumors shows that DNA deletions in 11p13 are rare.Semantic proximity Read ↗

Familial predisposition to Wilms tumor does not segregate with the WT1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.