Article
Direct pulsed field gel electrophoresis of Wilms' tumors shows that DNA deletions in 11p13 are rare.
Genes, chromosomes & cancer - 1 Mar 1991
Royer-Pokora B, Ragg S, Heckl-Ostreicher B, Held M, Loos U, Call K, Glaser T, Housman D, Saunders G, Zabel B
Abstract excerpt
In order to search for small tumor-specific deletions in 11p13 we analysed DNA isolated from 30 fresh Wilms' tumor (WT) samples with pulsed field gel electrophoresis. For these studies we have isolated new probes from the ends of several Notl fragments. Using these and previously described probes...
Topics
- Alleles
- Aniridia
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- DNA Probes
- DNA, Neoplasm
- Electrophoresis, Agar Gel
- Genes, Wilms Tumor
- Humans
- Kidney Neoplasms
- Methylation
- Restriction Mapping
- Syndrome
- Urogenital Abnormalities
- Wilms Tumor