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Article

Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophagus in Iran.

Oncogene - 1 Nov 2001

Sepehr A, Tanière P, Martel-Planche G, Zia'ee A A, Rastgar-Jazii F, Yazdanbod M, Etemad-Moghadam G, Kamangar F, Saidi F, Hainaut P

Abstract excerpt

Extremely high rates of squamous cell carcinoma of the esophagus (SCCE) are observed in Iran, reflecting unknown, genetic and/or epidemiological risk factors. Among genetic alterations in SCCE, TP53 mutations are the most frequent, vary among populations, and may provide clues on etiological mechanisms. We have analysed mutations in TP53 (exons 5-8) in 98 SCCE from Iran by temporal temperature gel electrophoresis...

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Identifiers

PMID: 11704866
DOI: 10.1038/sj.onc.1204912

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TP53

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Source receipt: pubmed, retrieved 7 Sept 2026.

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