Article
Relationship between genetic polymorphism of glutathione S-transferase-p1 and p53 protein accumulation in Iranian esophageal squamous cell carcinoma patients.
Indian journal of cancer - 1 Jan 2000
Sharifi R, Allameh A, Biramijamal F, Mohammadzadeh S H, Rasmi Y, Tavangar S M, Jamali-Zavarei M
Abstract excerpt
BACKGROUND: It has been reported that the activity of glutathione S-transferase (GST) is over-expressed in plasma and esophagus biopsies in Iranian patients suffering from esophageal squamous cell carcinoma (SCC). The aim of this study was to find out the frequency of GST-P genotypes in these patients. Moreover, the association of GST-P genotypes with p53 protein accumulation in esophageal epithelium was...
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