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Article

TP53 gene mutation profile in esophageal squamous cell carcinomas.

Cancer research - 1 Dec 1993

Audrézet M P, Robaszkiewicz M, Mercier B, Nousbaum J B, Bail J P, Hardy E, Volant A, Lozac'h P, Charles J F, Gouéron H

Abstract excerpt

Esophageal squamous cell carcinoma is a form of cancer occurring most commonly in males, particularly those living in some areas of Asia, Africa, and western Europe. In some of these tumors, a sequence alteration has been identified in the coding region of the TP53 gene which is known to inactivate the tumor suppressor function of its product. Using a GC clamp (i.e., a GC rich domain) denaturing gradient gel...

Topics

Adult
Aged
Base Sequence
Carcinoma, Squamous Cell
DNA Damage
Esophageal Neoplasms
Female
Genes, p53
Humans
Male
Middle Aged
Molecular Sequence Data

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Identifiers

PMID: 8242631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8242631-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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