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Article

TP53 gene mutation profile in esophageal squamous cell carcinomas.

Cancer research - 1 Dec 1993

Audrézet M P, Robaszkiewicz M, Mercier B, Nousbaum J B, Bail J P, Hardy E, Volant A, Lozac'h P, Charles J F, Gouéron H

Abstract excerpt

Esophageal squamous cell carcinoma is a form of cancer occurring most commonly in males, particularly those living in some areas of Asia, Africa, and western Europe. In some of these tumors, a sequence alteration has been identified in the coding region of the TP53 gene which is known to inactivate the tumor suppressor function of its product. Using a GC clamp (i.e., a GC rich domain) denaturing gradient gel...

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PMID: 8242631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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